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Clinical use of a diagnostic PCR for Francisella tularensis in patients with suspected ulceroglandular tularaemia.
Universitetssjukhuset, Örebro.
Umeå University, Faculty of Medicine, Clinical Microbiology. Umeå University, Faculty of Medicine, Clinical Microbiology, Clinical Bacteriology.
Universitetssjukhuset, Örebro.
2005 (English)In: Scandinavian Journal of Infectious Diseases, ISSN 0036-5548, E-ISSN 1651-1980, Vol. 37, no 11-12, 833-7 p.Article in journal (Refereed) Published
Abstract [en]

A retrospective analysis to evaluate the clinical use of a diagnostic PCR for Francisella tularensis in patients with suspected ulceroglandular tularaemia was performed. 154 samples, 129 from patients with definitive tularaemia and 25 from patients where tularaemia could be ruled out, were analysed. The diagnostic PCR had a specificity of 96%, a sensitivity of 78.3%, and a Positive Predictive Value of 99%. Especially samples from encrusted lesions, even up to 4 weeks old, in patients with tularaemia, were PCR positive to a high degree when taken properly. The diagnostic PCR is useful in suspected ulceroglandular tularaemia, giving a fast and accurate diagnosis.

Place, publisher, year, edition, pages
2005. Vol. 37, no 11-12, 833-7 p.
Identifiers
URN: urn:nbn:se:umu:diva-22748DOI: 10.1080/00365540500400951PubMedID: 16308216OAI: oai:DiVA.org:umu-22748DiVA: diva2:217952
Available from: 2009-05-18 Created: 2009-05-18 Last updated: 2017-12-13

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