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Interfering with cancer: a brief outline of advances in RNA interference in oncology
Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Immunology/Immunchemistry.
2004 (English)In: Tumour Biology, ISSN 1010-4283, E-ISSN 1423-0380, Vol. 25, no 5-6, 329-336 p.Article in journal (Refereed) Published
Abstract [en]

RNA interference (RNAi) is a potent and ubiquitous gene-silencing mechanism that is generating considerable excitement in the fields of molecular biology and gene therapy. It is now in widespread use for loss-of-function analysis in many diseases including cancer. Nevertheless, RNAi is still in its infancy, with new discoveries appearing on a monthly basis. This article presents a brief outline of the history and recent advances in RNAi with a specific focus on its potential in oncology.

Place, publisher, year, edition, pages
2004. Vol. 25, no 5-6, 329-336 p.
Keyword [en]
Molecular oncology, RNA interference
National Category
Cancer and Oncology
URN: urn:nbn:se:umu:diva-22757DOI: 10.1159/000081403PubMedID: 15627900OAI: diva2:218008
Available from: 2009-05-18 Created: 2009-05-18 Last updated: 2012-01-30Bibliographically approved

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