Grafting of silica with sulfobetaine polymers via aqueous reversible addition fragmentation chain transfer polymerization and its use as a stationary phase in HILIC
2009 (English)In: Journal of Separation Science, ISSN 1615-9306, E-ISSN 1615-9314, Vol. 32, no 12, 2008-2016 p.Article in journal (Refereed) Published
Porous silica particles of 3 mum diameter and 100 A nominal pore size were first activated for vinylic polymerization by functionalization with 3-methacryloyloxypropyl trimethoxysilane (MAPTMS) and thereafter dressed with zwitterionic grafts of the sulfoalkylbetaine type in the "grafting through" fashion by polymerizing 3-(2-(N-methacryloyloxyethyl)-N,N-dimethylammonio)propane sulfonate (SPE), using either free radical polymerization or controlled reversible addition fragmentation chain transfer polymerization (RAFT). Particles polymerized using RAFT had a lower overall coating which seemed to be more evenly distributed in the pore volume. Both approaches resulted in columns with similar separation properties in HILIC mode.
Place, publisher, year, edition, pages
Weinheim: WILEY-VCH Verlag GmbH & Co. KGaA , 2009. Vol. 32, no 12, 2008-2016 p.
Graft polymerization, HILIC, HPLC, Porous silica, RAFT, Stationary phase
IdentifiersURN: urn:nbn:se:umu:diva-23176DOI: 10.1002/jssc.200800554PubMedID: 19479757OAI: oai:DiVA.org:umu-23176DiVA: diva2:220793