Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer.
2009 (English)In: British journal of cancer, ISSN 1532-1827, Vol. 100, no 10, 1603-1607 p.Article in journal (Refereed) Published
Herein, we describe a novel approach in the search for prostate cancer biomarkers, which relies on the transcriptome within tumour exosomes. As a proof-of-concept, we show the presence of two known prostate cancer biomarkers, PCA-3 and TMPRSS2:ERG the in exosomes isolated from urine of patients, showing the potential for diagnosis and monitoring cancer patients status.
Place, publisher, year, edition, pages
2009. Vol. 100, no 10, 1603-1607 p.
IdentifiersURN: urn:nbn:se:umu:diva-23215DOI: 10.1038/sj.bjc.6605058PubMedID: 19401683OAI: oai:DiVA.org:umu-23215DiVA: diva2:221571