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Genomic deletion marking an emerging subclone of Francisella tularensis subsp. holarctica in France and the Iberian Peninsula.
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2007 (English)In: Applied and Environmental Microbiology, ISSN 0099-2240, Vol. 73, no 22, 7465-70 p.Article in journal (Refereed) Published
Abstract [en]

Francisella tularensis subsp. holarctica is widely disseminated in North America and the boreal and temperate regions of the Eurasian continent. Comparative genomic analyses identified a 1.59-kb genomic deletion specific to F. tularensis subsp. holarctica isolates from Spain and France. Phylogenetic analysis of strains carrying this deletion by multiple-locus variable-number tandem repeat analysis showed that the strains comprise a highly related set of genotypes, implying that these strains were recently introduced or recently emerged by clonal expansion in France and the Iberian Peninsula.

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2007. Vol. 73, no 22, 7465-70 p.
URN: urn:nbn:se:umu:diva-23396DOI: 10.1128/AEM.00646-07PubMedID: 17890329OAI: diva2:223652
Available from: 2009-06-13 Created: 2009-06-13 Last updated: 2009-06-13

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