Handheld resonance sensor instrumentation towards faster diagnosis of prostate cancer: stiffness measurements on a soft tissue phantom
2009 (English)In: IFMBE Proceedings of the World Congress on Medical Physics and Biomedical Engineering, Heidelberg: Springer , 2009, 808-811 p.Conference paper (Refereed)
Prostate cancer is the most common type of cancer among men. Standard methods for detecting and diagnosing prostate cancer are not sensitive enough. Radical prostatectomy is a procedure where the prostate is removed as a treatment for prostate cancer. Objectively measured prostate stiffness could be a clinical marker for prostate cancer and this could be accomplished with a stiffness sensitive resonance sensor. A future handheld pen-like resonance sensor instrument could be a valuable clinical tool for locating cancer during radical prostatectomy surgery and thus aid in the diagnosis and treatment. The aim of this study was to evaluate the concept of a handheld resonance sensor for stiffness measurements on a soft tissue phantom. For a handheld resonance sensor set-up the impression depth and speed of the sensor tip into the tissue are unknown. A theoretical model was derived to show that a stiffness sensitive parameter can be obtained independent of the impression depth and the impression speed. The theoretical result was verified on a soft tissue phantom made of gelatin with a silicon tumor inclusion. These results were promising for further studies and development of a handheld instrument towards faster diagnosis of prostate cancer.
Place, publisher, year, edition, pages
Heidelberg: Springer , 2009. 808-811 p.
, IFMBE Proceedings, ISSN 1680-0737 ; 25
handheld resonance sensor, stiffness, tissue phantom, prostate cancer
Medical Laboratory and Measurements Technologies
IdentifiersURN: urn:nbn:se:umu:diva-26235OAI: oai:DiVA.org:umu-26235DiVA: diva2:241017