Change search
ReferencesLink to record
Permanent link

Direct link
Toxicology and biological monitoring of metals
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
2009 (English)In: General and Applied Toxicology: volume 6, part thirteen: Toxicology of specific groups of substances / [ed] Bryan Ballantyne, Timothy C. Marrs and Tore Syversen, Wiley , 2009, 3Chapter in book (Other academic)
Abstract [en]

There are 67 elements classified as metals and the present chapter presents a review of the toxicology and evidence for useful biological monitoring of 29 of these elements and their various chemical compounds. Introductory sections of the chapter deals with general aspects of metal toxicology. Emphasis is given to the fundamental importance of speciation of metals. The chemical species is defined as the specific form of an element defined as to isotopic composition, electronic or oxidation state and /or complex or molecular structure. Consideration of specific chemical species is of fundamental importance in toxicology and biological monitoring. Advances in chemical analytical methods has made it possible in recent years to use biological monitoring i.e., repeated measurements of metallic compounds in tissues or biological fluids in order to evaluate occupational or environmental exposures and health risks. For all the elements dealt with in this chapter the importance of chemical species is considered when reviewing the uptake, metabolism and excretion; toxic effects and dose-response relationships; carcinogenicity; genotoxicity as well as biological monitoring. The following metals and their compounds are covered in the present chapter: Aluminium, Antimony, Arsenic, Barium, Beryllium, Bismuth, Cadmium, Chromium, Cobalt, Copper, Gallium and Semiconductor compounds, Germanium, Indium, Iron, Lead, Manganese, Mercury, Molybdenum, Nickel, Palladium, Platinum, Selenium, Silver, Tellurium, Thallium, Tin, Titanium, Tungsten and Zinc.

Place, publisher, year, edition, pages
Wiley , 2009, 3.
Keyword [en]
toxicology of metals, biological monitoring, biomarkers, human risk assessment
National Category
Pharmacology and Toxicology
URN: urn:nbn:se:umu:diva-30740DOI: 10.1002/9780470744307.gat145ISBN: 978-0-470-72327-2OAI: diva2:286432
Available from: 2010-01-14 Created: 2010-01-14 Last updated: 2011-03-03Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Nordberg, Gunnar F
By organisation
Occupational and Environmental Medicine
Pharmacology and Toxicology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 117 hits
ReferencesLink to record
Permanent link

Direct link