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New data favouring that neurotrophins are of importance in arthritis
Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB), Anatomy.
2009 (English)In: Arthritis Research & Therapy, ISSN 1478-6362, Vol. 11, no 4, 122- p.Article in journal (Other academic) Published
Abstract [en]

Neurotrophins are important in inflammation. In an article in Arthritis Research & Therapy, Barthel and collaborators give new information on the existence of neurotrophin production in the synovial tissue of arthritic joints. These findings, together with other recent findings, stress that neurotrophins should be considered important factors in arthritis. This is reinforced by the facts that they are also produced by articular chondrocytes and that receptors for these are present in the synovial tissue and on chondrocytes. The importance of neurotrophins in joints should be further studied, including examinations on the efficacy of interfering with their effects in arthritis.

Place, publisher, year, edition, pages
2009. Vol. 11, no 4, 122- p.
National Category
Medical and Health Sciences
URN: urn:nbn:se:umu:diva-31974DOI: 10.1186/ar2754PubMedID: 19678907OAI: diva2:300544
Available from: 2010-02-26 Created: 2010-02-26 Last updated: 2011-12-01Bibliographically approved

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