Change search
ReferencesLink to record
Permanent link

Direct link
Ischemia-induced repolarization response in relation to the size and location of the ischemic myocardium during short-lasting coronary occlusion in humans.
Umeå University, Faculty of Medicine, Public Health and Clinical Medicine, Medicine.
Umeå University, Faculty of Medicine, Public Health and Clinical Medicine, Medicine.
Show others and affiliations
2010 (English)In: Journal of Electrocardiology, ISSN 0022-0736, Vol. 43, no 2, 104-112 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The ventricular repolarization (VR) response to short-lasting coronary occlusion has been characterized by 3-dimensional vectorcardiography (VCG) in humans; the T vector loop becomes distorted and more circular. The purpose of this study was to relate these changes to the size of the myocardium at risk (MAR) and its location. METHODS: Continuous VCG was applied during transient coronary occlusion in 35 elective angioplasty patients, and the size of the MAR was estimated by single-photon emission computed tomography. Three VR aspects were assessed at baseline vs maximum ischemia: the ST segment, the T vector angles, and the T vector loop morphology. RESULTS: The T loop morphology changes were significantly associated with MAR size, but also dependent of its location. In contrast, the early phase of VR reflected by the ST segment responded to acute ischemia in relation to the MAR size independent of location. CONCLUSION: The VR changes were related both to the size and the location of the MAR and most pronounced during occlusion of the left anterior descending artery.

Place, publisher, year, edition, pages
2010. Vol. 43, no 2, 104-112 p.
Keyword [en]
Ventricular repolarization, Sudden cardiac death, Coronary artery, Vectorcardiography, Acute ischemia
National Category
Medical and Health Sciences
URN: urn:nbn:se:umu:diva-32943DOI: 10.1016/j.jelectrocard.2009.10.004PubMedID: 19959183OAI: diva2:306803
Available from: 2010-03-31 Created: 2010-03-31 Last updated: 2010-04-07Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Jensen, Steen MNäslund, Ulf
By organisation
In the same journal
Journal of Electrocardiology
Medical and Health Sciences

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 29 hits
ReferencesLink to record
Permanent link

Direct link