Supported ionic liquids in Burkholderia cepacia lipase-catalyzed asymmetric acylation
2010 (English)In: Journal of Molecular Catalysis B: Enzymatic, ISSN 1381-1177, Vol. 67, no 1-2, 129-134 p.Article in journal (Refereed) Published
Lipase PS from Burkholderia cepacia was successfully immobilized on Kynol™ ACC 507-15 active carbon cloth with and without ionic liquids as SILE catalysts. Activity, enantioselectivity and reuse of the catalysts were evaluated in the acylation of 1-phenylethanol with vinyl acetate in toluene and in hexane over the temperature range 25 - 60 °C. The presence of [EMIM][NTf2] clearly stabilized the enzyme against inactivation and preserved enantioselectivity in reuse in a process which is affected by the nature of the IL, solvent and substrate structure.
Place, publisher, year, edition, pages
Elsevier, 2010. Vol. 67, no 1-2, 129-134 p.
lipase, kinetic resolution, immobilization, supported ionic liquid catalyst
IdentifiersURN: urn:nbn:se:umu:diva-35216DOI: 10.1016/j.molcatb.2010.07.018ISI: 000282865800021OAI: oai:DiVA.org:umu-35216DiVA: diva2:337916