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Male infertility after mesh hernia repair: a prospective study
Department of Surgery, Clinical Sciences, Lund University and Lund University Hospital, Lund, Sweden.
CLINTEC, Division of Surgery, Karolinska Institute, Stockholm, Sweden.
Department of Surgery, Östersund Hospital.
CLINTEC, Division of Surgery, Karolinska Institute, Stockholm, Sweden.
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2011 (English)In: Surgery, ISSN 0039-6060, E-ISSN 1532-7361, Vol. 149, no 2, 179-184 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Several animal studies have raised concern about the risk for obstructive azoospermia owing to vasal fibrosis caused by the use of alloplastic mesh prosthesis in inguinal hernia repair. The aim of this study was to determine the prevalence of male infertility after bilateral mesh repair.

METHODS: In a prospective study, a questionnaire inquiring about involuntary childlessness, investigation for infertility and number of children was sent by mail to a group of 376 men aged 18-55 years, who had undergone bilateral mesh repair, identified in the Swedish Hernia Register (SHR). Questionnaires were also sent to 2 control groups, 1 consisting of 186 men from the SHR who had undergone bilateral repair without mesh, and 1 consisting of 383 men identified in the general population. The control group from the SHR was matched 2:1 for age and years elapsed since operation. The control group from the general population was matched 1:1 for age and marital status.

RESULTS: The overall response rate was 525 of 945 (56%). Method of approach (anterior or posterior), type of mesh, and testicular status at the time of the repair had no significant impact on the answers to the questions. Nor did subgroup analysis of the men </=40 years old reveal any significant differences.

CONCLUSION: The results of this prospective study in men do not support the hypothesis that bilateral inguinal hernia repair with alloplastic mesh prosthesis causes male infertility at a significantly greater rate than those operated without mesh.

Place, publisher, year, edition, pages
Elsevier, 2011. Vol. 149, no 2, 179-184 p.
Keyword [en]
spermatic cord structures, polypropylene mesh, vasal obstruction, hernioplasty, azoospermia, deferens, model, rats
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Research subject
URN: urn:nbn:se:umu:diva-35768DOI: 10.1016/j.surg.2010.04.027ISI: 000286713200005PubMedID: 20542309OAI: diva2:346982
Available from: 2010-09-02 Created: 2010-09-02 Last updated: 2015-11-13Bibliographically approved

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Nordin, PärGunnarsson, Ulf
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