Change search
ReferencesLink to record
Permanent link

Direct link
Transferrin C2, metal binding and Alzheimer's disease.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Psychiatry.
Show others and affiliations
1998 (English)In: NeuroReport, ISSN 0959-4965, E-ISSN 1473-558X, Vol. 9, no 2, 177-9 p.Article in journal (Refereed) Published
Abstract [en]

Significant associations between the transferrin (TF) variant C2 and a number of disorders suspected to be caused by oxygen free radicals have been reported. Thus an increased frequency of the TFC2 variant has been found in patients with Alzheimer's disease (AD), and it has been hypothesized that AD is caused by free radical damage due to defective binding of iron and aluminium by TFC2. In a study of 64 patients with AD from northern Sweden we were able to confirm the association between TFC2 and AD, but there were no significant differences between TFC2 and other TF variants with respect to the binding of iron and aluminium.

Place, publisher, year, edition, pages
1998. Vol. 9, no 2, 177-9 p.
URN: urn:nbn:se:umu:diva-36368PubMedID: 9507951OAI: diva2:353965
Available from: 2010-09-29 Created: 2010-09-29 Last updated: 2011-05-17

Open Access in DiVA

No full text


Search in DiVA

By author/editor
Adolfsson, Rolf
By organisation
In the same journal

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 38 hits
ReferencesLink to record
Permanent link

Direct link