Change search
ReferencesLink to record
Permanent link

Direct link
Caudate nucleus dopamine d(2) receptors in vascular dementia.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Psychiatry.
2002 (English)In: Dementia and Geriatric Cognitive Disorders, ISSN 1420-8008, E-ISSN 1421-9824, Vol. 14, no 1, 22-5 p.Article in journal (Refereed) Published
Abstract [en]

Caudate nucleus dopamine (DA) D(2) receptors were studied in patients with vascular dementia (VaD) and in a control group using [(3)H]raclopride as a radioligand. There was no significant difference in the number of DA D(2) receptors in the VaD group as compared with controls. The binding affinity was significantly lower in the VaD group. When the VaD group was subdivided into subjects with or without neuroleptic treatment, there were no differences in the numbers of receptors as compared with controls, and the significant differences in binding affinity remained for both VaD subgroups. The present results are discussed with reference to the previous finding of a reduced density of caudate nucleus DA uptake sites in the same VaD group and to results from studies on DA D(2) receptors in Alzheimer's disease and Parkinson's disease.

Place, publisher, year, edition, pages
2002. Vol. 14, no 1, 22-5 p.
URN: urn:nbn:se:umu:diva-36481PubMedID: 12053128OAI: diva2:354275
Available from: 2010-09-30 Created: 2010-09-30 Last updated: 2011-05-17

Open Access in DiVA

No full text


Search in DiVA

By author/editor
Allard, Per
By organisation
In the same journal
Dementia and Geriatric Cognitive Disorders

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 21 hits
ReferencesLink to record
Permanent link

Direct link