The impact of Haemophilus influenzae type b vaccination in Sweden
1996 (English)In: Scandinavian Journal of Infectious Diseases, ISSN 0036-5548, Vol. 28, no 2, 165-169 p.Article in journal (Refereed) Published
The number of patients with meningitis and bacteremia due to Haemophilus influenzae was studied in Sweden over the period 1987-1994. Conjugated H. influenzae type b vaccines were introduced in Sweden in 1992, and all children born after December 31, 1992, were offered vaccination free of charge. A rapid decline of H. influenzae meningitis and bacteraemia was observed in the autumn of 1993, when the expected peak incidence failed to appear. In the prevaccination period 1987-1991, the average annual incidence (cases/100,000) was 34.4 in children aged 0-4 years. In 1994, the annual incidence fell to 3.5. No significant decline was observed in older children or adults. There was a 92% reduction in the number of meningitis cases and an 83% reduction in cases of bacteraemia. A similar decline was noted in 2 regions which followed different strategies for the introduction of the vaccination programme.
Place, publisher, year, edition, pages
1996. Vol. 28, no 2, 165-169 p.
IdentifiersURN: urn:nbn:se:umu:diva-36910PubMedID: 8792484OAI: oai:DiVA.org:umu-36910DiVA: diva2:356671