umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Imaging of the guinea pig cochlea following round window gadolinium application
Center for Hearing and Communication Research, Karolinska Institutet, 171 76 Stockholm, Sweden.
Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden.
Center for Hearing and Communication Research, Karolinska Institutet, 171 76 Stockholm, Sweden.
Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden.
Show others and affiliations
2004 (English)In: NeuroReport, ISSN 0959-4965, E-ISSN 1473-558X, Vol. 15, no 12, 1927-1930 p.Article in journal (Refereed) Published
Abstract [en]

Precise, non-invasive determination of the aetiology and site of pathology of inner ear disorders is difficult. The aim of this study was to describe an alternative method for inner ear visualization, based on local application of the paramagnetic contrast agent gadolinium. Using a 4.7 T MRI scanner, high contrast images of all four cochlear turns were obtained 3.5 h after placing gadolinium on the round window membrane. Gadolinium cleared from the cochlea within 96 h. Auditory brainstem response measurements performed on a separate group of animals showed no significant threshold shifts after the application, indicating that gadolinium is non-toxic to the guinea pig cochlea.

Place, publisher, year, edition, pages
2004. Vol. 15, no 12, 1927-1930 p.
Keyword [en]
Gadolinium, Guinea pig, Hearing, Inner ear, MRI, Round window membrane
Identifiers
URN: urn:nbn:se:umu:diva-37175PubMedID: 15305139OAI: oai:DiVA.org:umu-37175DiVA: diva2:358228
Available from: 2010-10-21 Created: 2010-10-21 Last updated: 2017-12-12Bibliographically approved

Open Access in DiVA

No full text

PubMed

Search in DiVA

By author/editor
Laurell, Göran
In the same journal
NeuroReport

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 45 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf