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Ischaemic pre-conditioning means an increased adenosine metabolism with decreased glycolytic flow in ischaemic pig myocardium
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Anaesthesiology.
Department of Anaesthesiology and Intensive Care Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Anaesthesiology.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Cardiology.
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2010 (English)In: Acta Anaesthesiologica Scandinavica, ISSN 0001-5172, E-ISSN 1399-6576, Vol. 54, no 10, 1257-1264 p.Article in journal (Refereed) Published
Abstract [en]

This association between increased adenosine turnover and decreased glycolytic flow during prolonged ischaemia in response to IP can possibly be explained by the competitive effect for the metabolites from both glucose and adenosine metabolism for entering glycolysis. We conclude that this study provides support for an energy-metabolic explanation for the protective mechanisms of IP.

Place, publisher, year, edition, pages
2010. Vol. 54, no 10, 1257-1264 p.
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URN: urn:nbn:se:umu:diva-39664DOI: 10.1111/j.1399-6576.2010.02312.xPubMedID: 21039347OAI: oai:DiVA.org:umu-39664DiVA: diva2:394668
Available from: 2011-02-03 Created: 2011-02-03 Last updated: 2017-12-11Bibliographically approved

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Åberg, Anna-MajaAbrahamsson, PernillaWaldenström, AndersHauck, PhilipJohansson, GöranHaney, Michael
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