Relative biological effectiveness of 50-MV X-rays on jejunal crypt survival in vivo
1992 (English)In: Radiation Research, ISSN 0033-7587, Vol. 132, no 1, 112-114 p.Article in journal (Refereed) Published
Earlier in vitro studies of relative biological effectiveness (RBE) of 50-MV X rays show an RBE of approximately 1.1 compared to 4 MV. No difference in RBE has been found for 20-MV X rays or 50-MeV electrons. The higher RBE for 50 MV can be explained to some extent by the small high linear energy transfer contribution from photonuclear reactions at high X-ray energies. To investigate the validity of the results in vitro, a study of the RBE of 50-MV X rays has been performed in vivo using the jejunal crypt microcolony assay in mice. The reference radiation used in this case was 20-MV X rays. The results confirm the earlier in vitro studies. The RBE for 50-MV X rays was estimated to be 1.06, calculated as the ratio between the slopes of the response curves.
Place, publisher, year, edition, pages
Oak Brook, IL 60521 USA: Radiation Research Society , 1992. Vol. 132, no 1, 112-114 p.
Cancer and Oncology
IdentifiersURN: urn:nbn:se:umu:diva-39967DOI: 10.2307/3578341ISI: A1992JU54700016OAI: oai:DiVA.org:umu-39967DiVA: diva2:396933