umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Structural basis of signal-sequence recognition by the signal recognition particle 
Umeå University, Faculty of Science and Technology, Department of Chemistry.
Umeå University, Faculty of Science and Technology, Department of Chemistry.
Umeå University, Faculty of Science and Technology, Department of Chemistry.
Umeå University, Faculty of Medicine, Department of Medical Biochemistry and Biophysics.
Show others and affiliations
2011 (English)In: Nature Structural & Molecular Biology, ISSN 1545-9993, E-ISSN 1545-9985, Vol. 18, no 3, 389-391 p.Article in journal (Refereed) Published
Abstract [en]

The signal recognition particle (SRP) recognizes and binds the signal sequence of nascent proteins as they emerge from the ribosome. We present here the 3.0-Å structure of a signal sequence bound to the Methanococcus jannaschii SRP core. Structural comparison with the free SRP core shows that signal-sequence binding induces formation of the GM-linker helix and a 180° flip of the NG domain—structural changes that ensure a hierarchical succession of events during protein targeting.

Place, publisher, year, edition, pages
2011. Vol. 18, no 3, 389-391 p.
Identifiers
URN: urn:nbn:se:umu:diva-40342DOI: 10.1038/nsmb.1994OAI: oai:DiVA.org:umu-40342DiVA: diva2:399363
Note
Published online 20 February 2011Available from: 2011-02-22 Created: 2011-02-22 Last updated: 2017-12-11Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Authority records BETA

Hainzl, TobiasHuang, ShenghuaMeriläinen, GitteBrännström, KristofferSauer-Eriksson, A Elisabeth

Search in DiVA

By author/editor
Hainzl, TobiasHuang, ShenghuaMeriläinen, GitteBrännström, KristofferSauer-Eriksson, A Elisabeth
By organisation
Department of ChemistryDepartment of Medical Biochemistry and Biophysics
In the same journal
Nature Structural & Molecular Biology

Search outside of DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 330 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf