Adipose tissue has aberrant morphology and function in PCOS: enlarged adipocytes and low serum adiponectin, but not circulating sex steroids, are strongly associated with insulin resistance
2011 (English)In: Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, E-ISSN 1945-7197, Vol. 96, no 2, E304-E311 p.Article in journal (Refereed) Published
In PCOS, adipose tissue has aberrant morphology/function. Increased waist-to-hip ratio indicates abdominal/visceral fat accumulation, but this is not supported by MRI. Enlarged adipocytes and reduced serum adiponectin, together with a large waistline, rather than androgen excess, may be central factors in the pathogenesis/maintenance of insulin resistance in PCOS.
Place, publisher, year, edition, pages
2011. Vol. 96, no 2, E304-E311 p.
Medical and Health Sciences
Research subject Physical Chemistry
IdentifiersURN: urn:nbn:se:umu:diva-40811DOI: 10.1210/jc.2010-1290PubMedID: 21084397OAI: oai:DiVA.org:umu-40811DiVA: diva2:402972