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Adipose tissue has aberrant morphology and function in PCOS: enlarged adipocytes and low serum adiponectin, but not circulating sex steroids, are strongly associated with insulin resistance
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2011 (English)In: Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, E-ISSN 1945-7197, Vol. 96, no 2, E304-E311 p.Article in journal (Refereed) Published
Abstract [en]

In PCOS, adipose tissue has aberrant morphology/function. Increased waist-to-hip ratio indicates abdominal/visceral fat accumulation, but this is not supported by MRI. Enlarged adipocytes and reduced serum adiponectin, together with a large waistline, rather than androgen excess, may be central factors in the pathogenesis/maintenance of insulin resistance in PCOS.

Place, publisher, year, edition, pages
2011. Vol. 96, no 2, E304-E311 p.
National Category
Medical and Health Sciences
Research subject
Physical Chemistry
URN: urn:nbn:se:umu:diva-40811DOI: 10.1210/jc.2010-1290PubMedID: 21084397OAI: diva2:402972
Available from: 2011-03-10 Created: 2011-03-10 Last updated: 2011-10-31Bibliographically approved

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Olivecrona, Gunilla
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