Change search
ReferencesLink to record
Permanent link

Direct link
Detailed investigation of the role of common and low-frequency WFS1 variants in type 2 diabetes risk
Show others and affiliations
2010 (English)In: Diabetes, ISSN 0012-1797, E-ISSN 1939-327X, Vol. 59, no 3, 741-746 p.Article in journal (Refereed) Published
Abstract [en]

We identified six highly correlated SNPs that show strong and comparable associations with risk of type 2 diabetes, but further refinement of these associations will require large sample sizes (>100,000) or studies in ethnically diverse populations. Low frequency variants in WFS1 are unlikely to have a large impact on type 2 diabetes risk in white U.K. populations, highlighting the complexities of undertaking association studies with low-frequency variants identified by resequencing.

Place, publisher, year, edition, pages
2010. Vol. 59, no 3, 741-746 p.
URN: urn:nbn:se:umu:diva-40903DOI: 10.2337/db09-0920PubMedID: 20028947OAI: diva2:403517
Available from: 2011-03-14 Created: 2011-03-14 Last updated: 2015-04-22Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Hallmans, GöranRolandsson, OlovFranks, Paul W
By organisation
Nutritional ResearchFamily MedicineMedicine
In the same journal

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 52 hits
ReferencesLink to record
Permanent link

Direct link