Change search
ReferencesLink to record
Permanent link

Direct link
Increased response-time variability is associated with reduced inferior parietal activation during episodic recognition in aging.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Diagnostic Radiology. Umeå University, Faculty of Medicine, Department of Integrative Medical Biology (IMB).
Show others and affiliations
2008 (English)In: Journal of cognitive neuroscience, ISSN 0898-929X, E-ISSN 1530-8898, Vol. 20, no 5, 779-786 p.Article in journal (Refereed) Published
Abstract [en]

Intraindividual variability (IIV) in cognitive performance shares systematic associations with aging-related processes, brain injury, and neurodegenerative pathology. However, little research has examined the neural underpinnings of IIV, with no studies investigating brain correlates of IIV in relation to retrieval success. Using functional magnetic resonance imaging, we examined links between IIV, recognition memory performance, and blood oxygenation level dependent activations. Nineteen older adults (70-79 years) were presented with 80 words at encoding, with brain scans and response latencies obtained during subsequent recognition. An index of IIV, the intraindividual standard deviation (ISD), was computed across successful latency trials. Decreasing ISDs were systematically associated with better recognition, faster latencies, and increased activation in the inferior parietal cortex (BA 40). Demonstrated links between less behavioral variability and parietal activations are consistent with the known importance of the parietal cortex for retrieval success. In support of extant findings and theory from neuroscience, neuropsychology, and cognitive aging, the present results suggest that behavioral IIV represents a proxy for neural integrity.

Place, publisher, year, edition, pages
2008. Vol. 20, no 5, 779-786 p.
URN: urn:nbn:se:umu:diva-41154DOI: 10.1162/jocn.2008.20502PubMedID: 18201127OAI: diva2:404822
Available from: 2011-03-18 Created: 2011-03-18 Last updated: 2011-03-18

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Nyberg, Lars
By organisation
Diagnostic RadiologyDepartment of Integrative Medical Biology (IMB)
In the same journal
Journal of cognitive neuroscience

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 22 hits
ReferencesLink to record
Permanent link

Direct link