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[Autoimmune hepatitis often requires lifelong treatment]
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
2010 (Swedish)In: Läkartidningen, ISSN 0023-7205, Vol. 107, no 21, 1388-1391 p.Article in journal (Refereed) Published
Abstract [en]

Autoimmune hepatitis (AIH) is a rare disease with an incidence of around 1 / 100,000 inhabitants, and a prevalence rate of 16 / 100,000. As many as 30 % of AIH-patients already have liver cirrhosis at diagnosis. The diagnosis is established with liver function tests of hepatocellular pattern, presence of autoimmune antibodies, increased polyclonal IgG, and a compatible liver biopsy. Mostly, immune suppressive treatment with corticosteroids alone or in combination with azathioprine brings the disease into remission. In cirrhotic patients there is an increased risk of hepatocellular cancer (HCC) with a SIR of 23.

Place, publisher, year, edition, pages
2010. Vol. 107, no 21, 1388-1391 p.
Keyword [en]
Hepatit, autoimmun, Lever, Autoantikroppar, Vävnadsprov, Prevalens, Incidens, Könsfördelning, Immunsuppression, Prednisolon, Budesonid, Azatioprin, Karcinom, hepatocellulärt
Identifiers
URN: urn:nbn:se:umu:diva-41404PubMedID: 20645615OAI: oai:DiVA.org:umu-41404DiVA: diva2:405901
Available from: 2011-03-24 Created: 2011-03-24 Last updated: 2011-03-28Bibliographically approved

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Werner, MårtenDanielsson, Åke

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