Methods and processes for the reanalysis of the NINDS tissue plasminogen activator for acute ischemic stroke treatment trial
2008 (English)In: Clinical trials (London, England), ISSN 1740-7745, Vol. 5, no 4, 308-315 p.Article in journal (Refereed) Published
With new NIH requirements for data-sharing, the frequency of re-analysis of clinical trial data may increase substantially. This re-evaluation provides a blueprint for future re-evaluations of other trials. These best practices include re-analysis of the study data, after suitable replication, by an independent multidisciplinary committee, including a skilled statistical programmer analyst. Primary investigators should address significant errors determined in such re-analyses.
Place, publisher, year, edition, pages
2008. Vol. 5, no 4, 308-315 p.
IdentifiersURN: urn:nbn:se:umu:diva-41424DOI: 10.1177/1740774508094404PubMedID: 18697845OAI: oai:DiVA.org:umu-41424DiVA: diva2:406020