Weight loss after gastric bypass surgery in women is followed by a metabolically favorable decrease in 11beta-hydroxysteroid dehydrogenase 1 expression in subcutaneous adipose tissue
2010 (English)In: Journal of Clinical Endocrinology and Metabolism, ISSN 0021-972X, E-ISSN 1945-7197, Vol. 95, no 7, 3527-3531 p.Article in journal (Refereed) Published
Weight loss after gastric bypass surgery was followed by metabolically favorable changes in insulin sensitivity, circulating leptin and adiponectin, and peripheral glucocorticoid metabolism. A significant reduction in 11beta-HSD1 expression was observed in sc adipose tissue after weight loss. This suggests that up-regulation of 11beta-HSD1 is a consequence, rather than a cause, of obesity.
Place, publisher, year, edition, pages
2010. Vol. 95, no 7, 3527-3531 p.
IdentifiersURN: urn:nbn:se:umu:diva-41447DOI: 10.1210/jc.2009-2472ISI: 000279589600062PubMedID: 20410231OAI: oai:DiVA.org:umu-41447DiVA: diva2:406112