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Combinations of nonlabeled, 125I-labeled, and anti-idiotypic antiplacental alkaline phosphatase monoclonal antibodies at experimental radioimmunotargeting.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Diagnostic Radiology.
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1997 (English)In: Acta Radiologica, ISSN 0284-1851, E-ISSN 1600-0455, Vol. 38, no 6, 1087-1093 p.Article in journal (Refereed) Published
Abstract [en]

Neither a preinjection of nonlabeled H7 nor a postinjection of alpha H7 nor a combination of both strategies resulted in improved tumor/nontumor dose ratios compared to a single injection of labeled H7. The monoclonal antibody H7 has a rapid and high uptake, combined with a prolonged retention time in the tumors. The kinetic properties of H7 are different from antibodies targeting intracellular tumor antigens.

Place, publisher, year, edition, pages
1997. Vol. 38, no 6, 1087-1093 p.
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URN: urn:nbn:se:umu:diva-41887PubMedID: 9394676OAI: oai:DiVA.org:umu-41887DiVA: diva2:407991
Available from: 2011-04-01 Created: 2011-04-01 Last updated: 2017-12-11

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Johansson, LennartHietala, Sven-OlaRiklund, Katrine
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