Combinations of nonlabeled, 125I-labeled, and anti-idiotypic antiplacental alkaline phosphatase monoclonal antibodies at experimental radioimmunotargeting.
1997 (English)In: Acta Radiologica, ISSN 0284-1851, E-ISSN 1600-0455, Vol. 38, no 6, 1087-1093 p.Article in journal (Refereed) Published
Neither a preinjection of nonlabeled H7 nor a postinjection of alpha H7 nor a combination of both strategies resulted in improved tumor/nontumor dose ratios compared to a single injection of labeled H7. The monoclonal antibody H7 has a rapid and high uptake, combined with a prolonged retention time in the tumors. The kinetic properties of H7 are different from antibodies targeting intracellular tumor antigens.
Place, publisher, year, edition, pages
1997. Vol. 38, no 6, 1087-1093 p.
IdentifiersURN: urn:nbn:se:umu:diva-41887PubMedID: 9394676OAI: oai:DiVA.org:umu-41887DiVA: diva2:407991