Ebola virus infection inversely correlates with the overall expression levels of promyelocytic leukaemia (PML) protein in cultured cells
2003 (English)In: BMC Microbiology, ISSN 1471-2180, Vol. 3, 6- p.Article in journal (Refereed) Published
We have established a simple fixation and immunofluorescence staining procedure that allows specific co-detection and precise sub-cellular localization of the PML nuclear bodies and the Ebola virus encoded proteins NP, VP35 and VP40 in formaldehyde treated cells. Interferon-alpha treatment delays virus production in vitro. Intact PML bodies may play an anti-viral role in Ebola infected cells.
Place, publisher, year, edition, pages
2003. Vol. 3, 6- p.
IdentifiersURN: urn:nbn:se:umu:diva-42050DOI: 10.1186/1471-2180-3-6PubMedID: 12697055OAI: oai:DiVA.org:umu-42050DiVA: diva2:408449