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The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis
Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Clinical Bacteriology. Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR). Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS). (Sjöstedt)
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2010 (English)In: BMC Microbiology, ISSN 1471-2180, E-ISSN 1471-2180, Vol. 10, 227- p.Article in journal (Refereed) Published
Abstract [en]

This suggests that expression and surface localisation of PilA contribute to virulence in the highly virulent type A strain, while PilT was dispensable for virulence in the mouse infection model.

Place, publisher, year, edition, pages
2010. Vol. 10, 227- p.
Keyword [en]
live vaccine strain; pseudomonas-aeruginosa; neisseria-gonorrhoeae; twitching motility; biogenesis; proteins; novicida; gene; attenuation; emergence
National Category
Microbiology in the medical area
Identifiers
URN: urn:nbn:se:umu:diva-42616DOI: 10.1186/1471-2180-10-227ISI: 000283222300001PubMedID: 20796283OAI: oai:DiVA.org:umu-42616DiVA: diva2:409836
Available from: 2011-04-11 Created: 2011-04-11 Last updated: 2017-12-11Bibliographically approved

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Golovliov, IgorSjöstedt, AndersForsberg, Åke

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Forslund, Anna-LenaSalomonsson, Emelie NäslundGolovliov, IgorSjöstedt, AndersForsberg, Åke
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Umeå Centre for Microbial Research (UCMR)Molecular Infection Medicine Sweden (MIMS)Department of Molecular Biology (Faculty of Medicine)Clinical BacteriologyDepartment of Molecular Biology (Faculty of Science and Technology)
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Microbiology in the medical area

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