umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging.
Show others and affiliations
1998 (English)In: Science, ISSN 0036-8075, E-ISSN 1095-9203, Vol. 279, no 5349, 373-7 p.Article in journal (Refereed) Published
Abstract [en]

The bacterium Helicobacter pylori is the causative agent for peptic ulcer disease. Bacterial adherence to the human gastric epithelial lining is mediated by the fucosylated Lewis b (Leb) histo-blood group antigen. The Leb-binding adhesin, BabA, was purified by receptor activity-directed affinity tagging. The bacterial Leb-binding phenotype was associated with the presence of the cag pathogenicity island among clinical isolates of H. pylori. A vaccine strategy based on the BabA adhesin might serve as a means to target the virulent type I strains of H. pylori.

Place, publisher, year, edition, pages
1998. Vol. 279, no 5349, 373-7 p.
Identifiers
URN: urn:nbn:se:umu:diva-42931PubMedID: 9430586OAI: oai:DiVA.org:umu-42931DiVA: diva2:410776
Available from: 2011-04-14 Created: 2011-04-14 Last updated: 2017-12-11

Open Access in DiVA

No full text

PubMed

Search in DiVA

By author/editor
Arnqvist, AnnaBorén, Thomas
In the same journal
Science

Search outside of DiVA

GoogleGoogle Scholar

pubmed
urn-nbn

Altmetric score

pubmed
urn-nbn
Total: 94 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf