Prevalence of coeliac disease in Turner syndrome.
1999 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 88, no 9, 933-6 p.Article in journal (Refereed) Published
This study was undertaken to investigate the prevalence of coeliac disease in children and adolescents with Turner syndrome. Eighty-seven children and adolescents with Turner syndrome were screened for IgA-antiendomysium antibodies (EMA) and IgA-antigliadin antibodies (AGA), 5% (4/87) being found to be EMA-positive, and 15% (13/87) to have AGA levels above normal. Of the 10 patients who were either AGA- or EMA-positive and further investigated with intestinal biopsy, four manifested villous atrophy (i.e. all three of the EMA-positive patients, but only one of the seven AGA-positive patients). The results suggest EMA-positivity to be a good immunological marker for use in screening for coeliac disease, and such screening to be justified in patients with Turner syndrome.
Place, publisher, year, edition, pages
1999. Vol. 88, no 9, 933-6 p.
IdentifiersURN: urn:nbn:se:umu:diva-45334PubMedID: 10519331OAI: oai:DiVA.org:umu-45334DiVA: diva2:429235