Emergence of the trimethoprim resistance gene dfrD in Listeria monocytogenes BM4293.
1997 (English)In: Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, E-ISSN 1098-6596, Vol. 41, no 5, 1134-1136 p.Article in journal (Refereed) Published
The sequence of the trimethoprim resistance gene of the 3.7-kb plasmid (pIP823) that confers high-level resistance (MIC, 1,024 microg/ml) to Listeria monocytogenes BM4293 was determined. The gene was identical to dfrD recently detected in Staphylococcus haemolyticus MUR313. The corresponding protein, S2DHFR, represents the second class of high-level trimethoprim-resistant dihydrofolate reductase identified in gram-positive bacteria. We propose that trimethoprim resistance in L. monocytogenes BM4293 could originate in staphylococci.
Place, publisher, year, edition, pages
1997. Vol. 41, no 5, 1134-1136 p.
IdentifiersURN: urn:nbn:se:umu:diva-45533PubMedID: 9145882OAI: oai:DiVA.org:umu-45533DiVA: diva2:430099