Assessing the value of CAN-gene mutations using MALDI-TOF MS
2011 (English)In: Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, E-ISSN 1432-1335, Vol. 137, no 8, 1239-1244 p.Article in journal (Refereed) Published
Sjöblom et al./Wood et al. already showed that the vast majority of CAN-genes are mutated at very low frequency. Due to the fact that we only found one mutation in our cohort, we therefore assume that at the selected loci, mutations might be low-frequency events and therefore, more rarely detectable. However, further evaluation of the CAN-gene mutations in larger cohorts should be the aim of further studies.
Place, publisher, year, edition, pages
2011. Vol. 137, no 8, 1239-1244 p.
Breast cancer, CAN-genes, MALDI-TOF MS, Multiplex assay
Cancer and Oncology
Research subject Oncology
IdentifiersURN: urn:nbn:se:umu:diva-45826DOI: 10.1007/s00432-011-0990-4PubMedID: 21691751OAI: oai:DiVA.org:umu-45826DiVA: diva2:435139