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Assessing the value of CAN-gene mutations using MALDI-TOF MS
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Oncology.
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland.
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland.
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2011 (English)In: Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, E-ISSN 1432-1335, Vol. 137, no 8, 1239-1244 p.Article in journal (Refereed) Published
Abstract [en]

Sjöblom et al./Wood et al. already showed that the vast majority of CAN-genes are mutated at very low frequency. Due to the fact that we only found one mutation in our cohort, we therefore assume that at the selected loci, mutations might be low-frequency events and therefore, more rarely detectable. However, further evaluation of the CAN-gene mutations in larger cohorts should be the aim of further studies.

Place, publisher, year, edition, pages
2011. Vol. 137, no 8, 1239-1244 p.
Keyword [en]
Breast cancer, CAN-genes, MALDI-TOF MS, Multiplex assay
National Category
Cancer and Oncology
Research subject
Oncology
Identifiers
URN: urn:nbn:se:umu:diva-45826DOI: 10.1007/s00432-011-0990-4PubMedID: 21691751OAI: oai:DiVA.org:umu-45826DiVA: diva2:435139
Available from: 2011-08-17 Created: 2011-08-17 Last updated: 2017-12-08Bibliographically approved

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Tavelin, BjörnLenner, Per

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