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A nonlinear obsever for on-line estimation of the cerebrospinal fluid outflow restistance.
Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics.
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics. Umeå University, Faculty of Science and Technology, Centre for Biomedical Engineering and Physics (CMTF).
Umeå University, Faculty of Medicine, Department of Radiation Sciences, Radiation Physics. Umeå University, Faculty of Science and Technology, Centre for Biomedical Engineering and Physics (CMTF).
Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics.
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2008 (English)In: Automatica, ISSN 0005-1098, E-ISSN 1873-2836, Vol. 44, no 5, 1426-1430 p.Article in journal (Refereed) Published
Abstract [en]

Accurate estimates of the outflow resistance of the human cerebrospinal fluid system are important for the diagnosis of a medical condition known as hydrocephalus. In this paper we design a nonlinear observer which provides on-line estimates of the outflow resistance, to the best of our knowledge the first method to do so. The output of the observer is proven to globally converge to an unbiased estimate. Its performance is experimentally verified using the same apparatus used to perform actual patient diagnoses and a specially-designed physical model of the human cerebrospinal fluid system.

Place, publisher, year, edition, pages
Elsevier , 2008. Vol. 44, no 5, 1426-1430 p.
Keyword [en]
Nonlinear observers, Biomedical systems, Parameter estimation
Identifiers
URN: urn:nbn:se:umu:diva-46152DOI: 10.1016/j.automatica.2007.09.025OAI: oai:DiVA.org:umu-46152DiVA: diva2:437146
Available from: 2011-08-26 Created: 2011-08-26 Last updated: 2017-12-08Bibliographically approved

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Andersson, KennetAndersson, NinaShiriaev, Anton SEklund, Anders

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Manchester, IanAndersson, KennetAndersson, NinaShiriaev, Anton SEklund, Anders
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