Change search
ReferencesLink to record
Permanent link

Direct link
Lipid rafts clustering and signalling by listeriolysin O.
Molecular Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
2004 (English)In: Biochemical Society Transactions, ISSN 0300-5127, E-ISSN 1470-8752, Vol. 32, no Pt 5, 712-714 p.Article in journal (Refereed) Published
Abstract [en]

Listeriolysin O, the major virulent determinant of Listeria monocytogenes, is known for forming pores on cholesterol-rich membranes. In the present study, we reveal its other facet, rafts clustering. By immunofluorescence microscopy, we show that the glycosylphosphatidylinositol-anchored proteins CD14 and CD24, which normally exhibit uniform distribution on J774 cells, undergo clustering upon treatment with LLO. The non-raft marker transferrin receptor is unaffected by such treatment. Rafts clustering might explain the induction of tyrosine phosphorylation observed on LLO-treated cells.

Place, publisher, year, edition, pages
2004. Vol. 32, no Pt 5, 712-714 p.
URN: urn:nbn:se:umu:diva-46344DOI: 10.1042/BST0320712PubMedID: 15493995OAI: diva2:437899
Available from: 2011-08-30 Created: 2011-08-30 Last updated: 2011-08-30

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Gekara, N O
In the same journal
Biochemical Society Transactions

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 29 hits
ReferencesLink to record
Permanent link

Direct link