Common variation at 10p12.31 near MLLT10 influences meningioma risk
2011 (English)In: Nature Genetics, ISSN 1061-4036, Vol. 43, no 9, 825-827 p.Article in journal (Refereed) Published
To identify susceptibility loci for meningioma, we conducted a genome-wide association study of 859 affected individuals (cases) and 704 controls with validation in two independent sample sets totaling 774 cases and 1,764 controls. We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 x 10(-14)). This finding advances our understanding of the genetic basis of meningioma development.
Place, publisher, year, edition, pages
London: Nature America, Inc. , 2011. Vol. 43, no 9, 825-827 p.
IdentifiersURN: urn:nbn:se:umu:diva-47382DOI: 10.1038/ng.879OAI: oai:DiVA.org:umu-47382DiVA: diva2:443704