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Few sex differences in use of drugs for secondary prevention after stroke: a nationwide observational study
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine.
2011 (English)In: Abstracts 27th International Conference on Pharmacoepidemiology & Therapeutic Risk Management Hyatt Regency Chicago: Chicago, Illinois, USA August 14–17, 2011, Wiley , 2011, Vol. 20, S110-S110 p.Conference paper, Published paper (Refereed)
Abstract [en]

Background: Secondary preventive drug treatment after stroke is important to prevent further development of disease. Although recommendations for secondary prevention are the same for men and women, reality is not always in accordance with recommendations.

Objectives: This observational study intended to describe the differences between men and women in the use of secondary preventive drugs after ischemic stroke in terms of prescribing and continuous use. The purpose was also to investigate differences in patient and treatment related factors associated with drug use.

Methods: In this nationwide register - based study, the Swedish Stroke Register was linked to the Swedish Prescribed Drug Register for information on drugs prescribed for, and bought by, stroke patients. Background factors were included from the Stroke Register.

Results: Men were more often prescribed statins after stroke, 45.2% versus 33.8% (p<0.001). There were no differences in prescribing of antihypertensive or antithrombotic drugs. No differences were seen between the sexes regarding not continuing drug treatment after discharge (primary non - adherence). Women had a slightly higher persistence rate to antihypertensive treatment 2 years after discharge from hospital, 76.3% versus 71.9% for men (p<0.001), but there were no differences in persistence to antithrombotic or lipid - lowering treatments. The same factors were related to statin prescribing for both men and women. Factors associated to persistence to antihypertensive treatment were the same for both sexes except for a follow - up visit to hospital which was associated with increased persistence for men; age was associated with increased persistence and dissatisfaction with care was associated with decreased persistence for women.

Conclusions: This study showed small or no differences between men and women after stroke. Patients' use of secondary preventive drugs needs to be improved. Men and women do not have to be treated differently.

Place, publisher, year, edition, pages
Wiley , 2011. Vol. 20, S110-S110 p.
Series
Pharmacoepidemiology and Drug Safety, ISSN 1053-8569 ; Vol. 20 Suppl. 1
National Category
Pharmacology and Toxicology
Identifiers
URN: urn:nbn:se:umu:diva-47914DOI: 10.1002/pds.2206ISI: 000294946600245OAI: oai:DiVA.org:umu-47914DiVA: diva2:445593
Conference
27th International Conference on Pharmacoepidemiology & Therapeutic Risk ManagementHyatt Regency Chicago, Chicago, Illinois, USA August 14–17, 2011
Available from: 2011-10-04 Created: 2011-10-03 Last updated: 2011-10-04Bibliographically approved

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Sjölander, MariaEriksson, MarieGlader, Eva-Lotta
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