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From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics.
Department of Molecular Biology, The Scripps Center for Mass Spectrometry.
2007 (English)In: Journal of Proteome Research, ISSN 1535-3893, E-ISSN 1535-3907, Vol. 6, no 2, 459-68 p.Article in journal (Refereed) Published
Abstract [en]

Mass spectrometry (MS) is an established technology in drug metabolite analysis and is now expanding into endogenous metabolite research. Its utility derives from its wide dynamic range, reproducible quantitative analysis, and the ability to analyze biofluids with extreme molecular complexity. The aims of developing mass spectrometry for metabolomics range from understanding basic biochemistry to biomarker discovery and the structural characterization of physiologically important metabolites. In this review, we will discuss the techniques involved in this exciting area and the current and future applications of this field.

Place, publisher, year, edition, pages
2007. Vol. 6, no 2, 459-68 p.
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Natural Sciences
URN: urn:nbn:se:umu:diva-48247DOI: 10.1021/pr060505+PubMedID: 17269703OAI: diva2:448497
Available from: 2011-10-17 Created: 2011-10-12 Last updated: 2011-11-10Bibliographically approved

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Nordström, Anders
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