A Selective Intramolecular 5-exo-dig or 6-endo-dig Cyclization en Route to 2-Furanone or 2-Pyrone Containing Tricyclic Scaffolds
2011 (English)In: Journal of Organic Chemistry, ISSN 0022-3263, E-ISSN 1520-6904, Vol. 76, no 23, 9817-9825 p.Article in journal (Refereed) Published
Ringfused bicyclic 2-pyridones exhibit interesting biological properties against pili assembly in uropathogenic E. coli1 as well as curli formation2. In the strive for new ring-fused central fragments highly selective synthetic routes to the 2-furanone or 2-pyrone containing tricyclic scaffolds 1 and 2 have been developed.
Place, publisher, year, edition, pages
American Chemical Society (ACS), 2011. Vol. 76, no 23, 9817-9825 p.
IdentifiersURN: urn:nbn:se:umu:diva-49167DOI: 10.1021/jo201952pPubMedID: 22008034OAI: oai:DiVA.org:umu-49167DiVA: diva2:453249