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Thrombotic microangiopathy
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
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2011 (English)In: Transfusion and apheresis science, ISSN 1473-0502, E-ISSN 1878-1683, Vol. 45, no 2, 119-123 p.Article in journal (Refereed) Published
Abstract [en]

Thrombotic microangiopathy (TMA) is a histopathological feature of various diseases including thrombotic thrombocytopenic purpura (UP) and hemolytic uremic syndrome (HUS). There are many secondary causes of TMA, many of them could mimic TTP or HUS. This article presents a short overview on TMA. In conclusion TMA is the result of various etiology reasons and pathologic reactions with various clinical entities. It is important to focus on a thorough history including family history when deciding on a diagnosis. Analysis of ADAMTS 13 and ADAMTS 13-antibodies may help to decide continued therapy. (C) 2011 Elsevier Ltd. All rights reserved.

Place, publisher, year, edition, pages
Oxford: Pergamon , 2011. Vol. 45, no 2, 119-123 p.
Keyword [en]
Thrombotic microangiopathy, Hemolytic uremic syndrome, ADAMTS13, TMA, TTP, HUS
National Category
Hematology
Identifiers
URN: urn:nbn:se:umu:diva-50161DOI: 10.1016/j.transci.2011.07.002ISI: 000296406200003OAI: oai:DiVA.org:umu-50161DiVA: diva2:460081
Available from: 2011-11-29 Created: 2011-11-28 Last updated: 2017-12-08Bibliographically approved

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