Empty spiracles represses twin-of-eyeless in the Drosophila embryonic head
(English)Manuscript (preprint) (Other academic)
The specification of the eye-antennal disc primordium in the Drosophila embryo requires the expression of two paralogous Pax6 genes: twin of eyeless (toy) and eyeless (ey). toy is considered to be the first eye specification gene expressed in the regulatory network that governs eye formation and the gene that, in turn, activates eyeless. What regulates toy expression is, however, still unclear. We show, by misexpression and mutant analysis, that the head-specific gene empty spiracles alters the expression pattern of Toy in the head region around the visual primordia.
Drosophila, empty spiracles, eye development, Pax6, twin-of-eyeless
Research subject Molecular Biology
IdentifiersURN: urn:nbn:se:umu:diva-50725OAI: oai:DiVA.org:umu-50725DiVA: diva2:467819