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Studie av larynxpapillom i norra Sverige: två fall av onkogena HPV bland 26 patienter
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Otorhinolaryngology.
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Otorhinolaryngology.
Umeå University, Faculty of Medicine, Department of Clinical Microbiology, Virology. (Arcum)
Umeå University, Faculty of Medicine, Department of Clinical Microbiology.
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2011 (Swedish)In: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 108, no 21, 1187-1189 p.Article in journal (Refereed) Published
Abstract [en]

Laryngeal papilloma is associated with human papillomavirus (HPV) 6, 11, 16, 18 and 31. The variation in the frequency of surgical treatment between patients for the same subtypes of HPV is inconsistent and poorly understood. Comparisons of the female laryngeal papilloma group (n?=?8, median age 46 yrs) with the male (n= 18, median age 32 yrs) with respect to gender, age, time of disease, period of life for diagnosis, disease progression profile, frequency of surgery (CO2 laser) during time of disease, localisation of papilloma in the upper airway and HPV subtype did not reach significance. In contrast the comparison between the high frequency (Ž 1 treatment/yr, n?=?11, median age 31 yrs) and low frequency (<1 treatment/yr, n?=?15 median age 45 yrs) treatment groups with regard to the same parameters as the female-male comparison, showed a clear-cut higher median age in the low frequency group (P?=?0,01).

Abstract [sv]

Ingen signifikant skillnad mellan könen noterades i denna studie av en grupp patienter i Norrland där man jämfört kvinnor (n = 8, medianålder 46 år) och män (n = 18, me­dianålder 32 år) med larynxpapillom med avseende på aktuell ­ålder, sjukdomsduration, dia­gnosperiod i livet, sjukdomsutveckling, operationstillfällen under sjukdomsperioden, ­papillomlokalisation i luft­vägar och HPV-typ. Brytpunkten för hög respek­tive låg behandlingsfrekvens förlades till medelvärdet 1 behandling/år. Vid jämförelse mellan patienter med hög (≥ 1 behandling/år, n = 11, medianålder 31 år) respektive låg behandlingsfrekvens (< 1 behandling/år, n = 15, medianålder 45 år) ­registrerades signifikant ­högre ålder i gruppen med låg behandlingsfrekvens (P = 0,01).

Place, publisher, year, edition, pages
2011. Vol. 108, no 21, 1187-1189 p.
Keyword [sv]
Alfapapillomvirus, jämförande studie, struphuvudtumörer, papillom, papillomvirusinfektioner, könsfaktorer, Sverige
National Category
Cancer and Oncology
Identifiers
URN: urn:nbn:se:umu:diva-52951PubMedID: 21812242OAI: oai:DiVA.org:umu-52951DiVA: diva2:508186
Note

English title: A study of laryngeal papilloma in northern Sweden. Two cases of oncogenic HPV among 26 patients.

Available from: 2012-03-07 Created: 2012-03-07 Last updated: 2017-12-07Bibliographically approved

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Olofsson, KatarinaLoizou, ChristosEvander, MagnusMincheva-Nilsson, LuciaLaurell, Göran
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