Nutritional surveillance and weight loss in head and neck cancer patients
2012 (English)In: Supportive Care in Cancer, ISSN 0941-4355, E-ISSN 1433-7339, Vol. 20, no 4, 757-765 p.Article in journal (Refereed) Published
This retrospective single-institution cohort study aims to evaluate if therapeutic approach, tumour site, tumour stage, BMI, gender, age and civil status predict body weight loss and to establish the association between weight loss on postoperative infections and mortality. Consecutive patients with head and neck cancer were seen for nutritional control at a nurse-led outpatient clinic and followed-up for 2 years after radiotherapy. Demographic, disease-specific and nutrition data were collected from case records. The primary outcome measure was maximum body weight loss during the whole study period. The nadir of body weight loss was observed 6 months after radiotherapy. In total, 92 patients of 157 (59%) with no evidence of residual tumour after treatment received enteral nutrition. The mean maximum weight loss for patients receiving enteral nutrition and per oral feeding was 13% and 6%, respectively (p < 0.001). Using multivariate analysis, tumour stage (p < 0.001) was the only independent factor of maximum weight loss. Weight loss was not significantly related to risk for postoperative infection. Weight loss is frequently noted among head and neck cancer patients during and after treatment. Weight loss was not found to be associated with postoperative infections and mortality. Nutritional surveillance is important in all patients, but special attention should be given to those on enteral nutrition and those with more advanced disease.
Place, publisher, year, edition, pages
New York: Springer-Verlag New York, 2012. Vol. 20, no 4, 757-765 p.
Head and neck cancer, Radiotherapy, Enteral nutrition, Body weight loss, Nutrition, Postoperative infections
Cancer and Oncology
IdentifiersURN: urn:nbn:se:umu:diva-53929DOI: 10.1007/s00520-011-1146-4ISI: 000301525700011OAI: oai:DiVA.org:umu-53929DiVA: diva2:515265