Change search
ReferencesLink to record
Permanent link

Direct link
Nutritional surveillance and weight loss in head and neck cancer patients
Umeå University, Faculty of Medicine, Department of Clinical Sciences, Otorhinolaryngology.
2012 (English)In: Supportive Care in Cancer, ISSN 0941-4355, E-ISSN 1433-7339, Vol. 20, no 4, 757-765 p.Article in journal (Refereed) Published
Abstract [en]

This retrospective single-institution cohort study aims to evaluate if therapeutic approach, tumour site, tumour stage, BMI, gender, age and civil status predict body weight loss and to establish the association between weight loss on postoperative infections and mortality. Consecutive patients with head and neck cancer were seen for nutritional control at a nurse-led outpatient clinic and followed-up for 2 years after radiotherapy. Demographic, disease-specific and nutrition data were collected from case records. The primary outcome measure was maximum body weight loss during the whole study period. The nadir of body weight loss was observed 6 months after radiotherapy. In total, 92 patients of 157 (59%) with no evidence of residual tumour after treatment received enteral nutrition. The mean maximum weight loss for patients receiving enteral nutrition and per oral feeding was 13% and 6%, respectively (p < 0.001). Using multivariate analysis, tumour stage (p < 0.001) was the only independent factor of maximum weight loss. Weight loss was not significantly related to risk for postoperative infection. Weight loss is frequently noted among head and neck cancer patients during and after treatment. Weight loss was not found to be associated with postoperative infections and mortality. Nutritional surveillance is important in all patients, but special attention should be given to those on enteral nutrition and those with more advanced disease.

Place, publisher, year, edition, pages
New York: Springer-Verlag New York, 2012. Vol. 20, no 4, 757-765 p.
Keyword [en]
Head and neck cancer, Radiotherapy, Enteral nutrition, Body weight loss, Nutrition, Postoperative infections
National Category
Cancer and Oncology
URN: urn:nbn:se:umu:diva-53929DOI: 10.1007/s00520-011-1146-4ISI: 000301525700011OAI: diva2:515265
Available from: 2012-04-12 Created: 2012-04-10 Last updated: 2012-04-12Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full text

Search in DiVA

By author/editor
Laurell, Göran
By organisation
In the same journal
Supportive Care in Cancer
Cancer and Oncology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 44 hits
ReferencesLink to record
Permanent link

Direct link