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Detergent-free formation and physicochemical characterization of nanosized lipid-polymer complexes: lipodisq
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2012 (English)In: Angewandte Chemie International Edition, ISSN 1433-7851, E-ISSN 1521-3773, Vol. 51, no 19, 4653-4657 p.Article in journal (Refereed) Published
Abstract [en]

Lipodisq particles are polymer-lipid complexes formed by detergent-free methods. Lipodisq particles containing dimyristoylphosphatidylcholine (DMPC) are characterized by increased lipid ordering compared to a DMPC dispersion. The styrene and maleic acid groups of the polymer interact with the DMPC lipid chains in bilayers, as well as lipid headgroups in the Lipodisq periphery.

Place, publisher, year, edition, pages
2012. Vol. 51, no 19, 4653-4657 p.
Keyword [en]
calorimetry;EPR spectroscopy;lipids;membranes;polymers
National Category
Chemical Sciences
URN: urn:nbn:se:umu:diva-54405DOI: 10.1002/anie.201201355PubMedID: 22473824OAI: diva2:523687
Available from: 2012-04-25 Created: 2012-04-25 Last updated: 2012-06-18Bibliographically approved

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Gröbner, Gerhard
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Department of Chemistry
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