Swallowing function in Parkinson’s patients following Zona Incerta deep brain stimulation
2012 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 126, no 5, 350-356 p.Article in journal (Refereed) Published
Objective The purpose of the present study was to examine if there was a negative effect of caudal Zona Incerta deep brain stimulation (cZI DBS) on pharyngeal swallowing function in Parkinson’s patients (PD). There are no former reports on swallowing and cZI DBS.
Methods Eight patients (aged 49 to 71 years; median 62) were evaluated pre- and postoperatively, at six and 12 months after DBS surgery. Evaluation tools were Fiberoptic Endoscopic Evaluation of Swallowing examinations and patients’ self-assessments of the swallowing function including a visual analogue scale and quality of life related questions. The swallowing protocol included Rosenbeck’s Penetration-Aspiration Scale, Secretion Severity Scale and parameters for pre-swallow spillage, pharyngeal residue and pharyngeal clearance.
Results There was no clear-cut effect of neurostimulation postoperatively at six and 12 months on any of the swallowing parameters except for pre-swallow spillage which was slightly worsened in the stimulation on condition 12m postoperatively. The answers to the self assessment questions did not vary significantly.
Conclusions The effect of the stimulation on swallowing function varied among individuals but the overall outcome was that cZI DBS did not seem to have a negative influence on swallowing function in the eight patients studied.
Place, publisher, year, edition, pages
John Wiley & Sons, 2012. Vol. 126, no 5, 350-356 p.
Deep brain stimulation, caudal Zona Incerta, Dysphagia, Parkinson's disease, FEES, aspiration, swallowing function, L-dopa, complications
Otorhinolaryngology Surgery Neurology
Research subject Oto-Rhino-Laryngology
IdentifiersURN: urn:nbn:se:umu:diva-55468DOI: 10.1111/j.1600-0404.2012.01658.xOAI: oai:DiVA.org:umu-55468DiVA: diva2:526994