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Intracerebral infections as a complication of deep brain stimulation
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Neurosurgery.
2012 (English)In: Stereotactic and Functional Neurosurgery, ISSN 1011-6125, E-ISSN 1423-0372, Vol. 90, no 2, p. 92-96Article in journal (Refereed) Published
Abstract [en]

Background: Intracerebral infections after deep brain stimulation (DBS) are rare. The published material is limited to 2 case reports. A review of 20 publications of 3,818 patients focusing on complications of DBS did not reveal one single case. For that reason, we decided to present our own experience of 4 patients with this complication.

Objectives: To analyze and present our material regarding intracerebral infections after DBS.

Methods: Four patients with intracerebral infection after DBS were retrospectively analyzed. Results: The 4 patients exhibited signs of intracerebral infection 2-14 days after DBS for Parkinson's disease. CT and MRI verified signs of possible cerebral involvement. In 3 patients, positive cultures were obtained from the extracted electrodes. All patients recovered completely following treatment with antibiotics and removal of the implanted hardware. Two of the patients were later re-implanted.

Conclusions: Intracerebral infection is a rare complication of DBS. It does, however, occur occasionally and should be taken into consideration when evaluating the risks of DBS.

Copyright (c) 2012 S. Karger AG, Basel

Place, publisher, year, edition, pages
S. Karger, 2012. Vol. 90, no 2, p. 92-96
Keyword [en]
Abscess, Deep brain stimulation, Intracerebral infection
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:umu:diva-55688DOI: 10.1159/000335712ISI: 000303490800004OAI: oai:DiVA.org:umu-55688DiVA, id: diva2:528717
Available from: 2012-05-28 Created: 2012-05-28 Last updated: 2018-06-08Bibliographically approved

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