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Verbal fluency in patients receiving bilateral versus left-sided deep brain stimulation of the subthalamic nucleus for Parkinson's disease
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience.
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience.
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience.
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2012 (English)In: Journal of the International Neuropsychological Society, ISSN 1355-6177, E-ISSN 1469-7661, Vol. 18, no 3, 606-611 p.Article in journal (Refereed) Published
Abstract [en]

The purpose of this study was to investigate the relative effects of unilateral (left-sided) versus bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) on verbal fluency. To do this, 10 Parkinson's disease patients with predominantly bilateral motor symptoms who received bilateral STN DBS were compared with 6 patients suffering from predominantly unilateral symptoms who received STN DBS on the left side only. The results suggest that unilateral STN DBS of the speech dominant hemisphere is associated with significantly less declines in measures of verbal fluency as compared to bilateral stimulation. (JINS, 2012, 18, 606-611)

Place, publisher, year, edition, pages
Cambridge University Press, 2012. Vol. 18, no 3, 606-611 p.
Keyword [en]
Verbal fluency disorders, Basal ganglia, Psychological side effects, Stereotaxic techniques, Functional laterality, Movement disorders
National Category
Neurosciences
Identifiers
URN: urn:nbn:se:umu:diva-55671DOI: 10.1017/S1355617711001925ISI: 000303690500022OAI: oai:DiVA.org:umu-55671DiVA: diva2:529345
Available from: 2012-05-30 Created: 2012-05-28 Last updated: 2017-12-07Bibliographically approved

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Sjöberg, Richard LHäggström, BjörnHariz, Marwan ILinder, JanFredricks, AnnaBlomstedt, Patric
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