A grand challenge for educational research is to remove its weak link to practice. One of the strategies to confront these challenges can be through the use of Design-Based Research (DBR). A DBR approach includes working iterations of design, implementation and evaluation in real world learning contexts, making it especially suitable for research in Technology Enhanced Learning (TEL). This paper describes and contextualizes a workshop that points out the need to examine different design approaches and digital technology tools to explore TEL in educational practices. Since the goal of the workshop is to use multidiscipline perspectives of education and didactics (ED), computer science (CS), interaction design (ID), to show the complexity for supporting next generation learning, these perspectives will in the paper be described and put in relation to each other. What research questions within and in between the three perspectives should be included in a DBRapproach in order to inform and facilitate TELpractices. In the end, of the paper a multidisciplinary DBR-approach allowing a more holistic understanding of educational practices usin g TEL will be argued for.