Change search
ReferencesLink to record
Permanent link

Direct link
Up-to-date on mortality in COPD: report from the OLIN COPD study
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Medicine.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
Show others and affiliations
2012 (English)In: BMC Pulmonary Medicine, ISSN 1471-2466, Vol. 12, 1- p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: The poor recognition and related underdiagnosis of COPD contributes to an underestimation of mortality in subjects with COPD. Data derived from population studies can advance our understanding of the true burden of COPD. The objective of this report was to evaluate the impact of COPD on mortality and its predictors in a cohort of subjects with and without COPD recruited during the twenty first century.

METHODS: All subjects with COPD (n = 993) defined according to the GOLD spirometric criteria, FEV1/FVC < 0.70, and gender- and age-matched subjects without airway obstruction, non-COPD (n = 993), were identified in a clinical follow-up survey of the Obstructive Lung Disease in Northern Sweden (OLIN) Studies cohorts in 2002-2004. Mortality was observed until the end of year 2007. Baseline data from examination at recruitment were used in the risk factor analyses; age, smoking status, lung function (FEV1 % predicted) and reported heart disease.

RESULTS: The mortality was significantly higher among subjects with COPD, 10.9%, compared to subjects without COPD, 5.8% (p < 0.001). Mortality was associated with higher age, being a current smoker, male gender, and COPD. Replacing COPD with FEV1 % predicted in the multivariate model resulted in the decreasing level of FEV1 being a significant risk factor for death, while heart disease was not a significant risk factor for death in any of the models.

CONCLUSIONS: In this cohort COPD and decreased FEV1 were significant risk factors for death when adjusted for age, gender, smoking habits and reported heart disease.

Place, publisher, year, edition, pages
BioMed Central, 2012. Vol. 12, 1- p.
Keyword [en]
obstructive lung-disease, long-term mortality, pulmonary disease, Northern Sweden, follow-up, cardiovascular mortality, respiratory symptoms, smoking, prevalence, smokers
National Category
Environmental Health and Occupational Health
URN: urn:nbn:se:umu:diva-58346DOI: 10.1186/1471-2466-12-1ISI: 000313249000001PubMedID: 22230685OAI: diva2:547948
Available from: 2012-08-29 Created: 2012-08-29 Last updated: 2015-08-26Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Lindberg, AnneRönmark, Eva
By organisation
MedicineOccupational and Environmental Medicine
In the same journal
BMC Pulmonary Medicine
Environmental Health and Occupational Health

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 43 hits
ReferencesLink to record
Permanent link

Direct link