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Directed diversity-oriented synthesis. Ring-fused 5- to 10-membered rings from a common peptidomimetic 2-pyridone precursor.
Umeå University, Faculty of Science and Technology, Department of Chemistry.
Umeå University, Faculty of Science and Technology, Department of Chemistry. Umeå University, Faculty of Medicine, Umeå Centre for Microbial Research (UCMR).
Umeå University, Faculty of Medicine, Molecular Infection Medicine Sweden (MIMS).
Umeå University, Faculty of Science and Technology, Department of Chemistry.
2012 (English)In: Tetrahedron Letters, ISSN 0040-4039, E-ISSN 1359-8562, Vol. 53, no 45, 6022-6024 p.Article in journal (Refereed) Published
Abstract [en]

A variety of ring-fused 2-pyridone-based central fragments were prepared using a strategy inspired by diversity-oriented synthesis. The produced compounds are diverse, yet focused, analogs of biologically active peptidomimetic 2-pyridones.

Place, publisher, year, edition, pages
Elsevier, 2012. Vol. 53, no 45, 6022-6024 p.
Keyword [en]
Diversity-oriented synthesis, Medium-sized rings, Peptidomimetics, 2-Pyridone
National Category
Chemical Sciences
Identifiers
URN: urn:nbn:se:umu:diva-58566DOI: 10.1016/j.tetlet.2012.08.100OAI: oai:DiVA.org:umu-58566DiVA: diva2:549090
Available from: 2012-09-03 Created: 2012-09-03 Last updated: 2017-12-07Bibliographically approved

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Sellstedt, MagnusPrasad, G KrishnaKrishnan, K SyamAlmqvist, Fredrik
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Department of ChemistryUmeå Centre for Microbial Research (UCMR)Molecular Infection Medicine Sweden (MIMS)
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Tetrahedron Letters
Chemical Sciences

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