Change search
ReferencesLink to record
Permanent link

Direct link
Brain findings in relation to cognitive outcomes in preterm children at school age
Umeå University, Faculty of Social Sciences, Department of Psychology.
Umeå University, Faculty of Social Sciences, Department of Psychology.
Umeå University, Faculty of Social Sciences, Department of Psychology.
2012 (English)In: Developmental Medicine & Child Neurology, ISSN 0012-1622, E-ISSN 1469-8749, Vol. 54, 33-34 p.Article in journal, Meeting abstract (Refereed) Published
Abstract [en]

OBJECTIVES: To explore whether brain volumes in ex-preterm born children at school age relates to their cognitive abilities.

BACKGROUND: It is well established that a preterm birth is associated with an increased risk for cognitive deficits that often remain undetected until school age. Such deficits are likely caused by an atypical neurodevelopment. There is, however, relatively little known about the characterization of the preterm born children’s brain in relation to long-term cognitive performance.

METHODS: A sample of preterm children (n = 32) and typically developing fullterm children (n = 38) at 7-8-years underwent 3-Tesla magnetic resonance imaging (MRI) with additional synthetic MR for extraction of brain tissue. MR-findings were related to performance on the Wechsler Intelligence Scale for Children, 4th edition (WISC-IV).

RESULTS: The preterm children performed significantly poorer than fullterm peers on the WISC-IV in terms of total IQ (M = 95.1 and 103.5, respectively) and other measures. Overall, the total brain volume was positively correlated with general cognitive ability (total IQ). Additionally, a significant relation between grey matter (GM) and IQ was found for the preterm children. However, no association between white matter (WM) and IQ was found.

CONCLUSIONS: Even in a small sample of school-aged children with a history of birth comparatively close to term it was possible to detect a link between atypical brain volumes and cognitive functioning. The nature of these associations is discussed in terms of how GM and WM may contribute to long-term cognition deficits associated with a preterm birth.

Place, publisher, year, edition, pages
John Wiley & Sons, 2012. Vol. 54, 33-34 p.
National Category
URN: urn:nbn:se:umu:diva-59622OAI: diva2:555372
The European Academy of Childhood Disability, 24th Annual Meeting, 16-19 May 2012, Istanbul, Turkey

Supplement s3

Available from: 2012-09-19 Created: 2012-09-19 Last updated: 2016-06-13Bibliographically approved

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Domellöf, ErikJohansson, Anna-MariaRönnqvist, Louise
By organisation
Department of Psychology
In the same journal
Developmental Medicine & Child Neurology

Search outside of DiVA

GoogleGoogle Scholar
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Total: 77 hits
ReferencesLink to record
Permanent link

Direct link