Olsson, Jan Davidsson, Sabina Unemo, Magnus Mölling, Paula 2012 (English)In: Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), ISSN 0903-4641, E-ISSN 1600-0463, Vol. 120, no 10, 778-785Article in journal (Refereed) Published
The aim of this study was to determine antibiotic susceptibility of Propionibacterium acnes isolates from prostate. Prostate-derived P. acnes isolates (n = 24, Umeå & Örebro, Sweden, 2007-2010) and a panel of control strains (n = 25, Sweden) collected from skin and deep infections were assessed for resistance to penicillin G, piperacillin-tazobactam, imipenem, gentamicin, azithromycin, erythromycin, vancomycin, ciprofloxacin, moxifloxacin, tetracycline, tigecycline, fusidic acid, clindamycin, rifampicin, linezolid, daptomycin, trimethoprim-sulfamethoxazole, and metronidazole. In addition, the isolates were tested for inducible clindamycin resistance. All prostate derived P. acnes isolates displayed wild-type distribution of MIC-values, without evidence of acquired resistance. In the reference panel, 5 of 25 isolates had acquired macrolide resistance with cross-resistance to azithromycin, clindamycin, and erythromycin. In addition, one of these isolates was resistant to tetracycline.
CHRONIC BACTERIAL PROSTATITIS, RANDOMIZED CONTROLLED-TRIAL, STERNAL WOUND INFECTIONS, PELVIC PAIN SYNDROME, CARDIAC-SURGERY, ANTIMICROBIAL RESISTANCE, CLINICAL PRESENTATION, TRACT-INFECTIONS, VULGARIS, MANAGEMENT
National CategoryMedical and Health Sciences
Identifiersurn:nbn:se:umu:diva-59682 (URN)10.1111/j.1600-0463.2012.02905.x (DOI)22958285 (PubMedID)oai:DiVA.org:umu-59682 (OAI)diva2:556236 (DiVA)